REGULAR-SEASON SERIES HISTORY

LEADER 49ers lead all-time series, 7-6

STREAKS Chiefs have won 3 of last 4

LAST GAME 9/23/18: 49ers 27 at Chiefs 38

LAST GAME AT SITE 10/5/14: 49ers 22, Chiefs 17

TIME 4:25 PM ET

TV FOX: Kevin Burkhardt, Greg Olsen, Erin Andrews, Tom Rinaldi (field reporters)

Kansas City SiriusXM 135 or 385 and the SXM App

San Francisco SiriusXM 82 or 227 and the SXM App

CHIEFS NOTES:

LAST WEEK L 24-20 vs. Buffalo

COACH VS. OPP. Andy Reid: 8-4

PTS. FOR 29.8

OFFENSE 382.3

PASSING Patrick Mahomes: 151-229-1,736-17-4-106.1

RUSHING Clyde Edwards-Helaire: 59-256-4.3-2

RECEIVING Travis Kelce (TE): 41-455-11.1-7

PTS. AGAINST 24.8

DEFENSE 356.5

SACKS Chris Jones, L’Jarius Sneed (CB): 3

INTs Jaylen Watson (R): 1

TAKE/GIVE -1 (5/6)

PUNTING (NET) Tommy Townsend: 54.0 (49.8)

KICKING Harrison Butker: 15 (6/6 PAT; 3/4 FG)

QB PATRICK MAHOMES passed for 338 yards & 2 TDs vs. 2 INTs last week, his 33rdcareer game with 300+ pass yards, surpassing HOFer Dan Marino (32 games) for most-ever by player in 1st 6 seasons. Aims for 4th in row with 2+ TD passes & 95+ rating. Passed for 314 yards 3 TDs vs. 0 INTs for 115.5 rating in last reg. season meeting. Has 19 TDs vs. 3 INTs for 122.4 rating in 5 career reg. season starts vs. NFC West. Has 90+ rating in 6 of his past 7 road starts. • RB CLYDE EDWARDS-HELAIRE aims for 3rd in row on road with rush TD. Aims for his 6th in row vs. NFC with 70+ scrimmage yards & 5th in row vs. NFC with TD. • RB JERICK MCKINNON appeared in 16 games for SF (2020) & had 6 TDs (5 rush, 1 rec.). • TE TRAVIS KELCE had 8 catches for 108 yards last week, his 31st-career game with 100+ rec. yards, tied with HOFer Tony Gonzalez for the 2nd-most such games ever by TE. Aims for his 7th in row on road with TD catch. Has rec. TD in 2 of 3 career games vs. SF, incl. postseason. Had 8 catches for 114 yards in last reg. season meeting. Leads NFL with 7 rec. TDs this season. • WR JUJU SMITH-SCHUSTER had 5 catches for season-high 113 yards & 1st TD of season in Week 6. Has 5 catches in 3 of past 4. Had 81 rec. yards & TD catch in only career game vs. SF (9/22/19 w/ Pit.). • WR MECOLE HARDMAN had 2nd TD catch of season last week. • DT CHRIS JONES had sack & PD in Week 6. Had 3 PD in SB LIV vs. SF. Has 1.5+ sacks in 3 of his past 4 in reg. season vs. NFC West. • LB NICK BOLTON led team with season-high 13 tackles & had 2 TFL last week. Is 1 of 2 (Jordyn Brooks) with 9+ tackles in each of 1st 6 weeks this season.

49ERS NOTES:

LAST WEEK L 28-14 at Atlanta

COACH VS. OPP. Kyle Shanahan: 0-2

PTS. FOR 20.3

OFFENSE 340.2

PASSING Jimmy Garoppolo: 94-148-1,153-7-3-94.8

RUSHING Jeff Wilson: 81-400-4.9-2

RECEIVING Deebo Samuel: 27-345-12.8-2

PTS. AGAINST 14.8

DEFENSE 255.8

SACKS Nick Bosa: 6

INTs Talanoa Hufanga: 2

TAKE/GIVE -2 (7/9)

PUNTING (NET) Mitch Wishnowsky: 45.5 (40.4)

KICKING Robbie Gould: 31 (13/13 PAT; 6/9 FG)

QB JIMMY GAROPPOLO passed for 296 yards & 2 TDs vs. 2 INTs last week. Has 0 INTs & 100+ rating in 4 of his past 5 games at home. Passed for 251 yards & 2 TDs vs. 0 INTs for 114.7 rating in only career reg. season start vs. KC (9/23/18). • RB JEFF WILSON has 70+ scrimmage yards in 3 of his past 4 at home. • WR DEEBO SAMUEL had 7 catches for 79 yards last week. Has 7 TDs (4 rush, 3 rec.) in his past 6 at home. Aims for 7th in row at home with 75+ scrimmage yards. Had 5 catches & 92 scrimmage yards (53 rush, 39 rec.) in SB LIV vs. KC (2/2/20). • WR BRANDON AIYUK had 8 catches for 83 yards & 1st career game with 2 rec. TDs last week. Aims for his 3rd in row with 50+ rec. yards. • TE GEORGE KITTLE had season highs in catches (8) & rec. yards (83) last week. Had 5 catches for 79 yards in last reg. season meeting. • DL NICK BOSA has 2 sacks & 2 TFL in each of 1st 2 home games in 2022 & has 7 sacks in his past 6 at home. Had sack & FF in SB LIV vs. KC (2/2/20). Ranks tied-1st in NFC with 6 sacks in 2022. • DL DRAKE JACKSON ranks tied-1st among rookies with 3 sacks in 2022 & aims for his 3rd in row with sack. • DL CHARLES OMENIHU aims for his 4th in row with sack. • LB FRED WARNER led team with 10 tackles last week. Has 9+ tackles in 3 of his past 4 at home. Had 11 tackles, 2 TFL & PD in last reg. season meeting. Had TFL & INT in SB LIV vs. KC (2/2/20). • CB CHARVARIUS WARD had 38 PD & 4 INTs in 67 games, incl. playoffs, with KC (2018-21). • S TALANOA HUFANGA aims for his 3rd in row with 5+ tackles. Has 5 PD in 6 games in 2022.