Friday, October 29, 2021
6 pm ET | Boys Class 2A | West Lafayette (18-1-2) vs. Brebeuf Jesuit (12-7-2) 
8 pm ET | Boys Class A | Westview (16-5) vs. Providence (15-3-3)

Saturday, October 30, 2021
11 am ET | Girls Class A | Andrean (15-3-3) vs. Heritage Christian (14-8)
1:30 pm ET | Girls Class 2A | Mishawaka Marian (20-3) vs. Evansville Memorial (19-3-1)
4 pm ET | Girls Class 3A | Homestead (20-0) vs. Carmel (18-2-2)
6:30 pm ET | Boys Class 3A | Noblesville (19-1-1) vs. Carmel (16-3-2)