Week 2 of the 2022 season gets underway with the first-ever NFL regular-season game to air exclusively on Amazon Prime Video. On Thursday, September 15 (8:15 PM ET), the Kansas City Chiefs will host the Los Angeles Chargers in a pivotal, early-season AFC West showdown. This will mark the first of 15 Thursday Night Football games to air exclusively on Prime Video this season (Weeks 2-17, excluding Thanksgiving). The game will feature Al Michaels, Kirk Herbstreit and Kaylee Hartung on the call.

The Chiefs lead the all-time regular-season series, 65-57-1, including a 34-28 overtime victory on Thursday Night Football in their last meeting in Week 15 of the 2021 season. Quarterback PATRICK MAHOMES threw the game-winning 34-yard touchdown to tight end TRAVIS KELCE on the first drive of overtime. It was the third touchdown pass of the game for Mahomes – second to Kelce – as he totaled a season-high 410 passing yards in the win. Kelce posted a career-high 191 receiving yards on 10 catches.

Each team enters Thursday coming off Week 1 victories. The Chiefs went on the road to defeat Arizona, 44-21, as Mahomes threw for 360 yards and five touchdowns for a 144.2 rating. It marked his sixth-career game with at least five touchdown passes, tied with Pro Football Hall of Famer DAN MARINO (six) and BEN ROETHLISBERGER (six) for the fourth-most games all-time. Only DREW BREES (11), TOM BRADY (nine) and Pro Football Hall of Famer PEYTON MANNING (nine) have more. Kelce led the team with eight catches for 121 yards and a touchdown, his 30th-career game with at least 100 receiving yards, joining ROB GRONKOWSKI (32 games) and Pro Football Hall of Famer TONY GONZALEZ (31) as the only tight ends with at least 30 such games in NFL history.

Running back CLYDE EDWARDS-HELAIRE caught a career-high two touchdown passes in Week 1, while rookie running back ISIAH PACHECO rushed for his first-career touchdown. On defense, defensive tackle CHRIS JONES recorded his 11th-career forced fumble last week. He has totaled four sacks in his past two Thursday games. Defensive end CARLOS DUNLAP had a sack in his Chiefs debut on Kickoff Weekend and has 5.5 sacks in six career games against the Chargers. Linebacker NICK BOLTON, who led all rookies with 112 tackles in 2021, posted a team-high 10 tackles in Week 1.

The Chargers defeated the Raiders at home last week, 24-19. Quarterback JUSTIN HERBERT passed for 297 yards with three touchdowns and no interceptions for a 129.4 rating. It marked his ninth career game with at least three touchdown passes and no interceptions, tied with Mahomes for the most-ever by a player in his first three seasons. In four career games against Kansas City, Herbert has 13 touchdowns (10 passing, three rushing) and a 108.3 rating. He finished the 2021 season with at least 300 passing yards in each of his final five road games. Wide receiver MIKE WILLIAMS aims for his third in a row at Kansas City with at least 100 receiving yards and a touchdown catch. Running back AUSTIN EKELER tied for the league lead with 20 touchdowns last season and aims for his fourth in a row against the Chiefs with a score. Rookie fullback ZANDER HORVATH recorded a touchdown catch last week in his NFL debut.

Linebacker KHALIL MACK led the team with three sacks and had a forced fumble in his Chargers debut in Week 1. Since entering the league in 2014, Mack ranks tied for second among all players with 24 forced fumbles. Linebacker JOEY BOSA also recorded a forced fumble last week and added 1.5 sacks. He posted a sack and forced fumble in the teams’ last meeting and aims for his fifth in a row in primetime with a sack. Safety DERWIN JAMES tied for the team lead with six tackles in Week 1 and posted a sack, while cornerback ASANTE SAMUEL JR. recorded his third-career interception in the win. Samuel also had an interception in last year’s Week 3 meeting in Kansas City.  

The Chiefs are looking to begin 2-0 for the fifth time in the past six years, while the Chargers are aiming to win their first two games of a season for the first time since 2012.

CHARGERS NOTES:

QB JUSTIN HERBERT passed for 279 yards & 3 TDs vs. 0 INTs for 129.4 rating last week, his 9th-career game with 3+ TD passes & 0 INTs, tied with Patrick Mahomes for most-ever by player in 1st 3 seasons. Has 13 TDs (10 pass, 3 rush) vs. 2 INTs for 108.3 rating in 4 career games vs. KC. Aims for his 9th in row vs. division with 2+ TD passes. Aims for his 6th in row on road with 300+ pass yards. • RB AUSTIN EKELER had 72 scrimmage yards (36 rush, 36 rec.) in Week 1. Aims for his 4th in row vs. KC with TD & has TD in 8 of his past 9 vs. division. Had 441 scrimmage yards (110.3 per game) & 9 TDs (5 rush, 4 rec.) in 4 primetime games last season. • FB ZANDER HORVATH (rookie) had TD catch last week in NFL debut. • WR KEENAN ALLEN had 66 rec. yards last week. Has TD catch in 4 of his past 5 vs. KC. Has 3 rec. TDs in 3 career games on TNF. • WR MIKE WILLIAMS has 100+ rec. yards & TD catch in 2 of his past 3 vs. KC. Has rec. TD in 2 of his past 3 vs. division. • WR DEANDRE CARTER & TE GERALD EVERETT each had rec. TDs last week in LAC debuts. Everett had career-high 2 rec. TDs in only career game vs. KC (11/19/18 w/ LAR). • LB KHALIL MACK led team with 3 sacks & had FF last week in LAC debut, his 2ndcareer game with 3+ sacks. Aims for his 6th in row vs. KC with 0.5+ sacks. • LB JOEY BOSA had 1.5 sacks & FF in Week 1. Had sack & FF in last meeting. Had 0.5+ sacks in 6 of 7 road games last season & 5 of 6 division games. Aims for his 5th in row in primetime with sack & 3rd in row with FF. • S DERWIN JAMES tied for team lead with 6 tackles & had sack last week. • CB ASANTE SAMUEL JR. had 2 PD & INT in Week 1. Had INT in last road meeting.

CHIEFS NOTES:

QB PATRICK MAHOMES passed for 360 yards & 5 TDs vs. 0 INTs for 144.2 rating last week, his 6th-career game with 5+ TD passes, tied for 4th-most in NFL history. Passed for 410 yards & 3 TDs in last meeting & aims for his 3rd in row vs. LAC with 3+ TD passes. Has 9 TDs vs. INT for 114.3 rating in 4 career starts on Thursday. • RB CLYDE EDWARDS-HELAIRE had 74 scrimmage yards (42 rush, 32 rec.) & career best 2 TD catches in Week 1. Rushed for 100 yards & had rec. TD in last home meeting. • RB ISIAH PACHECO (rookie) rushed for 62 yards & TD last week in NFL debut. • TE TRAVIS KELCE led team with 8 catches for 121 yards & TD in Week 1, his 30thcareer game with 100+ rec. yards, becoming 3rd TE ever (Rob Gronkowski & HOFer Tony Gonzalez) with 30+ such games. Had 10 catches for career-high 191 rec. yards with 2 rec. TDs in last meeting & aims for his 4th in row vs. LAC with 90+ rec. yards. • WR JUJU SMITH-SCHUSTER had 6 catches for 79 yards last week in KC debut. Has 50+ rec. yards & TD catch in 2 of his past 3 in primetime. • WR MECOLE HARDMAN had TD catch in Week 1. Had rec. TD in last home meeting. • DT CHRIS JONES had PD & 11th-career FF last week. Had TFL in last meeting. Has 4 sacks in his past 2 Thursday games. Aims for his 3rd in row in primetime with 2+ PD. • DT TERSHAWN WHARTON had 5th-career sack in Week 1. Had FF in last meeting. • DE CARLOS DUNLAP had sack last week in KC debut. Has 5.5 sacks & 2 FFs in 6 career games vs. LAC. • LB NICK BOLTON led team with 10 tackles & had TFL in Week 1, his 4th-career game with 10+ tackles. Had 14 tackles & career-high 3 PD in last meeting. • CB L’JARIUS SNEED had 8 tackles, sack & PD last week. Had 2 TFL in last meeting.